Selegiline
author:admin source:admin published:2013-11-18 11:25:21
Product name: Selegiline
Description:
Selegiline (Anipryl, L-deprenyl, Eldepryl, Emsam, Zelapar) is a drug used for
the treatment of early-stage Parkinson's disease, depression and senile
dementia. In normal clinical doses it is a selective irreversible MAO-B
inhibitor. However, in larger doses it loses its specificity and also inhibits
MAO-A. Dietary restrictions are common for MAOI treatments, but special dietary
restrictions for lower doses have been found to be unnecessary, and dietary
restrictions appear to be unnecessary at standard doses when selegiline is
taken as Emsam, the transdermal patch form, as no adverse events due to diet
have ever been reported with Emsam. The drug was discovered by József Knoll et
al. inHungary.
Selegiline belongs to a class of drugs called phenethylamines. Selegiline is a
levomethamphetamine derivative with a propargyl group attached to the nitrogen
atom.