Midazolam
author:admin source:admin published:2013-11-18 13:29:47
Product name: Midazolam
CAS: 59467-70-8
Molecular formula: C22H13ClD4FN3O4
Molecular weight: 445.86
Description:
Midazolam (/mɪˈdæzəlæm/, marketed in English-speaking countries andMexicounder
the trade names Dormicum, Hypnovel, and Versed,) is a short-acting drug in the
benzodiazepine class developed by Hoffmann-La Roche in the 1970s. The drug is
used for treatment of acute seizures, moderate to severe insomnia, and for
inducing sedation and amnesia before medical procedures. It possesses
profoundly potent anxiolytic, amnestic, hypnotic, anticonvulsant, skeletal
muscle relaxant, and sedative properties. Midazolam has a fast recovery time
and is the most commonly used benzodiazepine as a premedication for sedation;
less commonly it is used for induction and maintenance of anesthesia.
Flumazenil, a benzodiazepine antagonist drug, can be used to treat an overdose
of midazolam, as well as to reverse sedation. However, flumazenil can trigger
seizures in mixed overdoses and in benzodiazepine-dependent individuals, so is
not used in most cases.