Mecobalamin
author:admin source:admin published:2013-11-18 16:32:43
Product name: Mecobalamin
CAS: 13422-55-4
Molecular formula: C63H91CoN13O14P
Molecular weight: 1344.38
Description:
Methylcobalamin (mecobalamin, MeCbl, or MeB12) is a cobalamin, a form of
vitamin B12. It differs from cyanocobalamin in that the cyanide is replaced by
a methyl group.Methylcobalamin features an octahedral cobalt(III) centre.
Methylcobalamin can be obtained as bright red crystals. From the perspective of
coordination chemistry, methylcobalamin is notable as a rare example of a
compound that contains metal-alkyl bonds. Nickel-methyl intermediates have been
proposed for the final step of methanogenesis.
Methylcobalamin is
equivalent physiologically to vitamin B12, and can be used to prevent or treat
pathology arising from a lack of vitamin B12 (vitamin B12 deficiency), such as
pernicious anemia.
Methylcobalamin is
also used in the treatment of peripheral neuropathy, diabetic neuropathy, and
as a preliminary treatment for amyotrophic lateral sclerosis.