Rifabutin
author:admin source:admin published:2013-11-18 16:34:52
Product name: Rifabutin
CAS: 72559-06-9
Molecular formula: C46H62N4O11
Molecular weight: 847
Description:
Rifabutin (Rfb) is a bactericidal antibiotic drug primarily used in the
treatment of tuberculosis. The drug is a semi-synthetic derivative of rifamycin
S. Its effect is based on blocking the DNA-dependent RNA-polymerase of the
bacteria. It is effective against Gram-positive and some Gram-negative
bacteria, but also against the highly resistant Mycobacteria, e.g.
Mycobacterium tuberculosis, M. leprae, and M. avium intracellulare.