ketoconazole
author:admin source:admin published:2013-11-29 09:50:25
Product name: ketoconazole
CAS: 65277-42-1
Molecular formula: C26H28Cl2N4O4
Molecular weight:531.43
Description:Ketoconazole is a synthetic, imidazole-derived antifungal
medication used primarily to treat fungal infections. Ketoconazole is sold commercially
as a tablet for oral administration, and in a variety of formulations, such as
creams and shampoos, for topical administration.
The less toxic and
generally more effective triazole antifungal agents fluconazole and
itraconazole are usually preferred for internal use. The European Medicines
Agency's Committee on Medicinal Products for Human Use (CHMP) has recommended
that a ban be imposed on the use of ketoconazole for systemic use in humans
throughout the European Union, after concluding that the risk of serious liver
injury from systemic ketoconazole outweights its benefits.