Octocrylene
author:admin source:admin published:2013-11-29 14:54:21
Product name: Octocrylene
CAS: 6197-30-4
Molecular formula:C24H27NO2
Molecular weight:361.48
Description:Octocrylene
is an organic compound used as an ingredient in sunscreens and cosmetics. It is
an ester formed by the condensation of a diphenylcyanoacrylate with
2-ethylhexanol. It is a viscous, oily liquid that is clear and colorless.
The extended
conjugation of the acrylate portion of the molecule absorbs UVB and short-wave
UVA (ultraviolet) rays with wavelengths from 280 to 320 nm, protecting the skin
from direct DNA damage. The ethylhexanol portion is a fatty alcohol, adding
emollient and oil-like (water resistant) properties.
This organic
compound can penetrate into the skin where it acts as a photosensitizer. This
results in an increased production of free radicals under illumination. Free
radicals are known to induce indirect DNA damage, and an increased
concentration of free radicals might have contributed to the increased
incidence of malignant melanoma in sunscreen-users compared to non-users (see
Epidemiology of malignant melanoma)[weasel words][citation needed]. The only
evidence suggesting a relationship between sunscreen and malignant melanoma is
correlational, and thus cannot be used to establish a causal relationship.