Lactoferrin (LF)
author:admin source:admin published:2013-12-01 17:38:55
Product name: Lactoferrin (LF)
CAS: 146897-68-9
Description: Lactoferrin (LF),
also known as lactotransferrin (LTF), is a multifunctional protein of the
transferrin family. Lactoferrin is a globular glycoprotein with a molecular mass
of about 80 kDa that is widely represented in various secretory fluids, such as
milk, saliva, tears, and nasal secretions. Lactoferrin is also present in
secondary granules of PMN and is secreted by some acinar cells. Lactoferrin can
be purified from milk or produced recombinantly. Human colostrum ("first
milk") has the highest concentration, followed by human milk, then cow
milk (150 mg/L).
Lactoferrin is one
of the components of the immune system of the body; it has antimicrobial
activity (bacteriocide, fungicide) and is part of the innate defense, mainly at
mucoses. In particular, lactoferrin provides antibacterial activity to human
infants. Lactoferrin interacts with DNA and RNA, polysaccharides and heparin,
and shows some of its biological functions in complexes with these ligands.