Heparin Sodium
author:admin source:admin published:2013-04-24 16:34:00
Product Name: Heparin
Sodium
CAS No.:9041-08-01
Description:
Heparin is a
heterogenous group of straight-chain anionic mucopolysaccharides, called
glycosaminoglycans having anticoagulant properties. Although others may be
present, the main sugars occurring in heparin are: (1) α-L-iduronic acid
2-sulfate, (2) 2-deoxy-2-sulfamino-α-D-glucose 6-sulfate, (3) β-D-glucuronic
acid, (4) 2-acetamido-2-deoxy-α-D-glucose, and (5) α-L-iduronic acid. These
sugars are present in decreasing amounts, usually in the order (2) > (1)
> (4) > (3) > (5), and are joined by glycosidic linkages, forming
polymers of varying sizes. Heparin is strongly acidic because of its content of
covalently linked sulfate and carboxylic acid groups. In heparin sodium, the
acidic protons of the sulfate units are partially replaced by sodium ions.
Usage: It is a
preparation containing the sodium salt of a sulphated glucosaminoglycan present
in mammalian tissues. On complete hydrolysis, it liberates D-glucosamine,
D-glucuronic acid, L-iduronic acid, acetic acid and sulphuric acid.